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Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody
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产品编号 TMAC-03431
别名 Progesterone Receptor (p-Ser294), Progesterone Receptor (p-S294), p-Progesterone Receptor (Ser294), p-Progesterone Receptor (S294)
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Progesterone Receptor (Ser294)。Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody 可用于 WB。
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody
还可以产品编号 TMAC-03431 别名 Progesterone Receptor (p-Ser294), Progesterone Receptor (p-S294), p-Progesterone Receptor (Ser294), p-Progesterone Receptor (S294)
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Progesterone Receptor (Ser294)。Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,230 | 5日内发货 |
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| 产品描述 | Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB. |
| 别名 | Progesterone Receptor (p-Ser294), Progesterone Receptor (p-S294), p-Progesterone Receptor (Ser294), p-Progesterone Receptor (S294) |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of extracts from 293 cells treated with Etoposide using Phospho-Progesterone Receptor (Ser294) antibody TMAC-03431. The lane on the right is treated with the antigen-specific peptide. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition,progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of serine 294 (G-R-S(p)-P-L) derived from Human Progesterone Receptor |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 99 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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