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Ethoxylated hydrogenated castor oil

产品编号 T9718 CAS 61788-85-0

Ethoxylated hydrogenated castor oil 是一种聚乙二醇与天然蓖麻油的混合物，可用于水包油 (o/w) 乳浊液的乳化和增溶，是动物实验的良好助溶剂。

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Ethoxylated hydrogenated castor oil Chemical Structure

Ethoxylated hydrogenated castor oil, CAS 61788-85-0

规格	价格/CNY	货期
500 mg	￥ 296	现货
1 g	￥ 418	现货
5 g	￥ 756	现货

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生物活性

化学信息

存储 & 溶解度

参考文献

产品描述

Ethoxylated hydrogenated castor oil is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions.

体内活性

Nearly 20% of Ethoxylated hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake[1]. 20% Ethoxylated hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice[2]. Ethoxylated hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females[2].

分子量	N/A
CAS No.	61788-85-0

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

H2O: 100 mg/mL

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

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参考文献

1. Heni Rachmawati, et al. The In Vitro-In Vivo Safety Confirmation of PEG-40 Hydrogenated Castor Oil as a Surfactant for Oral Nanoemulsion Formulation. Sci Pharm. 2017 Mar 31;85(2):18. doi: 10.3390/scipharm85020018. 2. PEG-40 hydrogenated Castor Oil: Does It Benefit The Skin?

剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

剂量

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动物数量

第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

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