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gp130/IL6ST Protein, Mouse, Recombinant (hFc)

产品编号 TMPY-05793

gp130/IL6ST Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is Q00560.

gp130/IL6ST Protein, Mouse, Recombinant (hFc)

产品编号 TMPY-05793

gp130/IL6ST Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is Q00560.

规格	价格	库存
5 μg	¥ 815	6-8日内发货
10 μg	¥ 1,350	6-8日内发货
20 μg	¥ 2,260	6-8日内发货
50 μg	¥ 3,290	6-8日内发货
100 μg	¥ 4,430	6-8日内发货
200 μg	¥ 8,230	6-8日内发货
500 μg	¥ 18,800	6-8日内发货

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产品信息

生物活性	Measured by its ability to bind recombinant IL6(Native)/Biotin in a functional ELISA.
产品描述	gp130/IL6ST Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is Q00560.
种属	Mouse
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q00560
别名	interleukin 6 signal transducer,gp130,D13Ertd699e,CD130,BB405851,AA389424,5133400A03Rik
蛋白构建	A DNA sequence encoding the mouse IL6ST (NP_034690.3) (Met1-Glu617) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 23
蛋白纯度	> 90 % as determined by SDS-PAGE.
分子量	93.38 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.