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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Ceruloplasmin Polyclonal Antibody

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货号 TMAB-04259

Anti-Ceruloplasmin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ceruloplasmin。Anti-Ceruloplasmin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Ceruloplasmin Polyclonal Antibody

Anti-Ceruloplasmin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04259

Anti-Ceruloplasmin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ceruloplasmin。Anti-Ceruloplasmin Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Ceruloplasmin Polyclonal Antibody is a Rabbit antibody targeting Ceruloplasmin. Anti-Ceruloplasmin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Note=Colocalizes with GCP1 in secretory intracellular compartments.
组织特异性Expressed by the liver and secreted in plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Caeruloplasmin is a copper binding plasma glycoprotein consisting of a single polypeptide chain. It has a molecular weight of 132kDa and occurs in plasma at a concentration of 150-500 mg/L. Although the physiological functions of Caeruloplasmin are not fully understood it is implicated in a number of possible functions. 95% of plasma copper is bound to Caeruloplasmin, implying some involvement in copper transport. Caeruloplasmin has been described as both an oxidant and an antioxidant, its exact role or roles in this respect are not clear. Plasma levels of Caeruloplasmin are elevated after inflammation and trauma and it is therefore classified as an acute phase protein. The measurement of Caeruloplasmin in plasma is useful in the diagnosis of Wilson’s disease, where levels are greatly reduced. Caeruloplasmin is extremely labile in plasma and rapidly degrades to 115kDa and 19kDa fragments. The age of plasma samples should therefore be taken into account when interpreting immunological analysis of caeruloplasmin.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Ceruloplasmin
抗原种属
Human
基因名称
CP
基因ID
1356
蛋白名称
Ceruloplasmin
Uniprot ID
P00450
功能
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense.
化学信息
分子量Theoretical: 120 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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