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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90)

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货号 TMAB-07398

Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90) 是一种 Mouse 抗体，靶向 human CD274 (B7-H1, PD-L1)。Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90) 可用于 FCM。

Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90)

Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07398

Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90) 是一种 Mouse 抗体，靶向 human CD274 (B7-H1, PD-L1)。Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,860
5日内发货
200 μg
¥ 5,590
5日内发货
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产品介绍

生物活性
产品描述
Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90) is a Mouse antibody targeting human CD274 (B7-H1, PD-L1). Anti-human CD274 (B7-H1, PD-L1) Antibody (9X90) can be used in FCM.
Ig Type
IgG1
克隆号
9X90
反应种属
Human
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein.
组织特异性Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M PBS (pH7.4).
研究背景This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
抗原信息
基因名称
CD274
基因ID
29126
蛋白名称
Programmed cell death 1 ligand 1
功能
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
化学信息
分子量Theoretical: 32 kDa. Actual: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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