Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T28072 | MLN-3897
化合物MLN-3897
|
1010731-97-1 | 98% |
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MLN-3897 是一种具有口服活性的 CCR1 拮抗剂,对于 125I-MIP-1α 与 THP-1 细胞膜的结合,Ki 为 2.3 nM。 MLN-3897 抑制 Akt 信号转导和 MM 细胞存活和增殖。 | ||||
T12419L | PF-04634817
化合物 T12419L
|
1228111-63-4 | 98% |
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PF-0463481 is safe and well-tolerated and has the potential for the study of diabetic nephropathy. PF-0463481 is an effective and orally active dual CCR2/CCR5 an... | ||||
T10756 | Cenicriviroc Mesylate
化合物 T10756
|
497223-28-6 | 98% |
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Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory and antiinfective activity. | ||||
TN2951 | 3-(hydroxymethyl)cyclopentanone
化合物 TN2951
|
113681-11-1 | 98% |
|
3-Hydroxymethylcyclopentanone is a precursor to synthesize methyl epijasmonate. 3-Hydroxymethylcyclopentanone compounds, which are useful as intermediates in the... | ||||
T10710 | CCR1 antagonist 9
化合物 T10710
|
1220026-26-5 | 98% |
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CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay). | ||||
T11521 | GW 766994
化合物 T11521
|
408303-43-5 | 98% |
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GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment. | ||||
T11472L | Molibresib besylate
化合物 T11472L
|
1895049-20-3 | 98% |
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Molibresib besylate is an inhibitor of BET bromodomain (IC50: 32.5-42.5 nM). | ||||
TQ0182 | MK-0812
化合物MK-0812
|
624733-88-6 | 98% |
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MK-0812 is an effective and specific CCR2 antagonist. | ||||
T14373 | AZD2423
化合物 T14373
|
1229603-37-5 | 98% |
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AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM for C... | ||||
T17274 | YM022
化合物 T17274
|
145084-28-2 | 98% |
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YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist. YM022 can inhibit gastrin-induced gastric acid secretion and histi... | ||||
TN3119 | 5-Hydroxy-7,8-dimethoxyflavanone
5-羟基-7,8-二甲氧基黄烷酮
|
113981-49-0 | 98% |
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5-Hydroxy-7,8-dimethoxyflavanone 是从穿心莲叶和根中分离出来的,具有抗炎活性。 | ||||
T10711 | CCR2 antagonist 1
化合物 T10711
|
1683534-96-4 | 98% |
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CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM). | ||||
T12076L | ML218
化合物 T12076L
|
1346233-68-8 | 98% |
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ML218 inhibits the burst activity in the subthalamic nucleus (STN) neurons. ML218 is an effective, selective, and orally active inhibitor of T-type Ca2+ channel ... | ||||
T14307 | Aplaviroc
化合物 T14307
|
461443-59-4 | 98% |
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Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW. | ||||
T10709 | CCR1 antagonist 7
化合物 T10709
|
2446154-74-9 | 98% |
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CCR1 antagonist 7 (compound 16r) 是CCR1的拮抗剂,IC50值为 4 nM。 | ||||
T11704 | JAK-IN-3
化合物 T11704
|
1400876-94-9 | 98% |
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JAK-IN-3 is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively. | ||||
T14899 | CCR1 antagonist 8
化合物 T14899
|
1295298-26-8 | 98% |
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CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay). | ||||
T10714 | CCR5 antagonist 1
化合物 T10714
|
716354-86-8 | 98% |
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CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication. | ||||
T2386 | Pirfenidone
吡非尼酮
|
53179-13-8 | 98% |
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Pirfenidone 是一种抗纤维化剂,可减弱纤维细胞中CCL2和CCL12的产生。它可抑制细胞生长,并能降低人胶质瘤细胞系中的TGF-β2蛋白水平,具有抗炎活性。 | ||||
T16111 | ML604086
化合物ML604086
|
850330-18-6 | 98% |
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ML604086 是选择性CCR8抑制剂,抑制循环T 细胞上 CCL1 与 CCR8 结合,还抑制 CCL1 介导的趋化性并提高细胞内 Ca2 浓度。 |