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Perforin-1/PRF1 Protein, Mouse, Recombinant (His)
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货号 TMPH-02824
别名 Prf1, Pfp, Perforin-1, P1, Lymphocyte pore-forming protein, Cytolysin
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
其他形式的 “Perforin-1/PRF1 Protein, Mouse, Recombinant (His)”:
Perforin-1/PRF1 Protein, Mouse, Recombinant (His)
一键复制产品信息 很棒可置换缓冲液
货号 TMPH-02824 别名 Prf1, Pfp, Perforin-1, P1, Lymphocyte pore-forming protein, Cytolysin
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 825 | 3日内发货 | |
| 10 μg | ¥ 1,360 | 现货 | |
| 20 μg | ¥ 2,290 | 现货 | |
| 50 μg | ¥ 3,460 | 20日内发货 | |
| 100 μg | ¥ 4,750 | 20日内发货 | |
| 200 μg | ¥ 6,830 | 20日内发货 | |
| 500 μg | ¥ 10,800 | 20日内发货 | |
| 1 mg | ¥ 16,000 | 20日内发货 |
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产品介绍
生物活性
化学信息
储存&溶解度
| 产品描述 | Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. |
| 种属 | Mouse |
| 表达系统 | E. coli |
| 标签 | N-6xHis |
| 蛋白编号 | P10820 |
| 氨基酸序列 | PCYTATRSECKQKHKFVPGVWMAGEGMDVTTLRRSGSFPVNTQRFLRPDRTCTLCKNSLMRDATQRLPVAITHWRPHSSHCQRNVAAAKVHSTEGVAREAAANINNDWRVGLDVNPRPEANMRASVAGSHSKVANFAAEKTYQDQYNFNSDTVECRMYSFRLVQKPPLHLDFKKALRALPRNFNSSTEHAYHRLISSYGTHFITAVDLGGRISVLTALRTCQLTLNGLTADEVGDCLNVEAQVSIGAQASVSSEYKACEEKKKQHKMATSFHQTYRERHVEVLGGPLDSTHDLLFGNQATPEQFSTWTASLPSNPGLVDYSLEPLHTLLEEQNPKREALRQAISHYIMSRARWQNCSRPCRSGQHKSSHDSCQCECQDSKVTNQDCCPRQRGLAHLVVSNFRAEHLWGDYTTATDAYLKVFFGGQEFRTGVVWNNNNPRWTDKMDFENVLLSTGGPLRVQVWDADYGWDDDLLGSCDRSPHSGFHEVTCELNHGRVKFSYHAKCLPHLTGGTCLEYAPQGLLGDPPGNRSGAVW |
| 蛋白构建 | 21-554 aa |
| 蛋白纯度 | > 85% as determined by SDS-PAGE.  |
| 缓冲液 | Lyophilized from a 0.2 μm sterile filtered 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0. |
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | Prf1, Pfp, Perforin-1, P1, Lymphocyte pore-forming protein, Cytolysin |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 63.9 kDa (predicted) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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