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Anti-CD59a Antibody-APC (1M258)
还可以产品编号 TMAY-03434A
Anti-CD59a Antibody-APC (1M258) 是一种 APC-conjugated Rabbit 抗体，靶向 CD59a。Anti-CD59a Antibody-APC (1M258) 可用于 FCM。
Anti-CD59a Antibody-APC (1M258)
Anti-CD59a Antibody-APC (1M258)
还可以产品编号 TMAY-03434A
Anti-CD59a Antibody-APC (1M258) 是一种 APC-conjugated Rabbit 抗体，靶向 CD59a。Anti-CD59a Antibody-APC (1M258) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD59a Antibody-APC (1M258) is a APC-conjugated Rabbit antibody targeting CD59a. Anti-CD59a Antibody-APC (1M258) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1M258 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse CD59a expression on BABL/c bone marrow erythroid cells. Cells were stained with APC-conjugated anti-Mouse CD59a. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of erythroid cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD59a (rM CD59a; TMPY-02266; NP_001104530.1; Met1-Lys95) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins. It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Mouse CD59a Protein (TMPY-02266) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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