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IgG3 Protein, Human, Recombinant

IgG3 Protein, Human, Recombinant

产品编号 TMPY-02895
别名: IGHG3

IgG3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 31.2 kDa and the accession number is P01860.

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IgG3 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
100 μg ¥ 1,630 5日内发货
1 mg ¥ 7,510 5日内发货
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产品目录号及名称: IgG3 Protein, Human, Recombinant (TMPY-02895)
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产品描述 IgG3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 31.2 kDa and the accession number is P01860.
种属 Human
表达系统 HEK293 Cells
标签 Tag Free
蛋白编号 P01860
别名 IGHG3
蛋白构建 The Human IgG3 Fc region (P01860) (Glu 99-Lys 377) was expressed and purified.
蛋白纯度 ≥ 96 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
分子量 31.2 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 IGHG3 (Immunoglobulin Heavy Constant Gamma 3 (G3m Marker), also known as IgG3) is a Protein Coding gene. Ig gamma-3 chain C region is a protein that in humans is encoded by the IGHG3 gene. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Murine immunoglobulin G (IgG) plays an important role in mediating protective immune responses to malaria. Diseases associated with IGHG3 include Heavy Chain Disease and Gamma Heavy Chain Disease. Among its related pathways are IL4-mediated signaling events and the Creation of C4 and C2 activators.

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Keywords

IgG3 Protein, Human, Recombinant IGHG-3 IGHG3 IGHG 3 recombinant recombinant-proteins proteins protein

 

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