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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LXR beta Polyclonal Antibody

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货号 TMAB-08460

Anti-LXR beta Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LXR beta。Anti-LXR beta Polyclonal Antibody 可用于 WB。

Anti-LXR beta Polyclonal Antibody

Anti-LXR beta Polyclonal Antibody

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货号 TMAB-08460

Anti-LXR beta Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LXR beta。Anti-LXR beta Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-LXR beta Polyclonal Antibody is a Rabbit antibody targeting LXR beta. Anti-LXR beta Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Ubiquitous.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human LXR beta
抗原种属
Human
基因名称
NR1H2
基因ID
7376
蛋白名称
Oxysterols receptor LXR-beta
Uniprot ID
P55055
功能
Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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