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Anti-DUOX2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DUOX2。Anti-DUOX2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,ELISA。
Anti-DUOX2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DUOX2。Anti-DUOX2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,170 | 5日内发货 | |
100 μL | ¥ 1,970 | 5日内发货 | |
200 μL | ¥ 2,790 | 5日内发货 |
产品描述 | Anti-DUOX2 Polyclonal Antibody is a Rabbit antibody targeting DUOX2. Anti-DUOX2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
Ig Type | IgG |
交叉反应 | (predicted:Human,Mouse,Rat,Dog) |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Apical cell membrane. Localizes to the apical membrane of epithelial cells. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Dual oxidase 2 (DUOX2), also designated NADPH thyroid oxidase 2, p138 thyroid oxidase or large NOX2, localizes to the apical membrane of epithelial cells. DUOX1, also designated NADPH thyroid oxidase or large NOX1, and DUOX2 are multi-pass membrane proteins predominantly expressed in thyrocytes, tracheal surface epithelial cells as well as thyroid, colon, duodenum, trachea and bronchium. DUOX1 and DUOX2 generate hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. In mucosa, DUOX proteins are involved in thyroid hormone biosynthesis and lactoperoxidase-mediated antimicrobial defense. Defects in the gene encoding for DUOX2 cause congenital hypothyroidism (CH), a disorder characterized by a defect in hydrogen peroxide production in the thyroid gland. |
免疫原 | KLH conjugated synthetic peptide: human DUOX2 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Thyroid axis |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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