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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MADD Antibody (3F623)

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货号 TMAB-08504

Anti-MADD Antibody (3F623) 是一种 Rabbit 抗体，靶向 MADD。Anti-MADD Antibody (3F623) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-MADD Antibody (3F623)

Anti-MADD Antibody (3F623)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08504

Anti-MADD Antibody (3F623) 是一种 Rabbit 抗体，靶向 MADD。Anti-MADD Antibody (3F623) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MADD Antibody (3F623) is a Rabbit antibody targeting MADD. Anti-MADD Antibody (3F623) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3F623
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Highly expressed in fetal brain and kidney; adult testis, ovary, brain and heart. Isoform 5 is constitutively expressed in all tissues. Isoform 7 is expressed in fetal liver and in several cancer cell lines.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Guanyl-nucleotide exchange factor that regulates small GTPases of the Rab family.Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms.
抗原信息
免疫原
A synthesized peptide: human MADD
抗原种属
Human
基因名称
MADD
基因ID
8567
蛋白名称
MAP kinase-activating death domain protein
Uniprot ID
Q8WXG6
功能
Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Isoform 5 shows increased cell proliferation and isoform 2 shows decreased. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis); isoform 1 is susceptible to inducing apoptosis, isoform 5 is resistant and isoform 3 and isoform 4 have no effect.
化学信息
分子量Theoretical: 183 kDa. Actual: 230 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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