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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Rad17 (Ser656) Antibody (7H829)

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货号 TMAB-11207

Anti-Phospho-Rad17 (Ser656) Antibody (7H829) 是一种 Rabbit 抗体，靶向 Phospho-Rad17 (Ser656)。Anti-Phospho-Rad17 (Ser656) Antibody (7H829) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Phospho-Rad17 (Ser656) Antibody (7H829)

Anti-Phospho-Rad17 (Ser656) Antibody (7H829)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11207

Anti-Phospho-Rad17 (Ser656) Antibody (7H829) 是一种 Rabbit 抗体，靶向 Phospho-Rad17 (Ser656)。Anti-Phospho-Rad17 (Ser656) Antibody (7H829) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Rad17 (Ser656) Antibody (7H829) is a Rabbit antibody targeting Phospho-Rad17 (Ser656). Anti-Phospho-Rad17 (Ser656) Antibody (7H829) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
7H829
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Note=Phosphorylated form redistributes to discrete nuclear foci upon DNA damage.
组织特异性Overexpressed in various cancer cell lines and in colon carcinoma (at protein level). Isoform 2 and isoform 3 are the most abundant isoforms in non irradiated cells (at protein level). Ubiquitous at low levels. Highly expressed in testis, where it is expressed within the germinal epithelium of the seminiferous tubuli. Weakly expressed in seminomas (testicular tumors).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage.
抗原信息
免疫原
A synthesized peptide: human RAD17 around the phosphorylation site of S656
抗原种属
Human
基因名称
RAD17
基因ID
5884
蛋白名称
Cell cycle checkpoint protein RAD17
Uniprot ID
O75943
功能
Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and C12orf32/RHINO onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
化学信息
分子量Theoretical: 77 kDa. Actual: 85 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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