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Anti-ACACA Antibody (3I598)

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产品编号 TMAB-00029

别名 Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC

Anti-ACACA Antibody (3I598) 是一种 Rabbit 抗体，靶向 ACACA。Anti-ACACA Antibody (3I598) 可用于 IF,IHC-Fr,WB。

Anti-ACACA Antibody (3I598)

Anti-ACACA Antibody (3I598)

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Rating icon 还可以
产品编号 TMAB-00029 别名 Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC

Anti-ACACA Antibody (3I598) 是一种 Rabbit 抗体，靶向 ACACA。Anti-ACACA Antibody (3I598) 可用于 IF,IHC-Fr,WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-ACACA Antibody (3I598) is a Rabbit antibody targeting ACACA. Anti-ACACA Antibody (3I598) can be used in IF,IHC-Fr,WB.
别名Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC
Ig Type
IgG
克隆号
3I598
交叉反应
Human,Mouse,Rat
验证活性
Sample:
Lane 1: Mouse Brain Lysates
Lane 2: Human K562 cell Lysates
Primary: Anti-Acetyl CoA Carboxylase 1 (ACC1) (TMAB-00029) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 265 kDa
Observed band size: 265 kDa
verifiedActivity
应用IFIHC-FrWB
推荐剂量
WB: 1:500-1000; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Acetyl CoA Carboxylase 1(ACC1)
抗原种属
Human
基因名称
ACACA
基因ID
32
蛋白名称
Acetyl-CoA carboxylase 1
Uniprot ID
Q13085
研究领域
Integration of energy metabolism,Metabolism of lipids and lipoproteins,Synthesis,Integration of energy,Lipid metabolism,Mitochondrial markers,Fatty acid oxidation,Lipid metabolism,Mitochondrial
功能
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
化学信息
分子量Theoretical: 265 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Acetyl-Coenzyme A carboxylase α (ACC-α)Acetyl-Coenzyme A carboxylase a (ACC-a)ACC-αACCαACC-alphaACCalphaACC-aACCAACC 1

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