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Anti-FSTL1 Antibody (6R820)
还可以产品编号 TMAY-01333
Anti-FSTL1 Antibody (6R820) 是一种 Rabbit 抗体，靶向 FSTL1。Anti-FSTL1 Antibody (6R820) 可用于 ICC/IF。
Anti-FSTL1 Antibody (6R820)
Anti-FSTL1 Antibody (6R820)
还可以产品编号 TMAY-01333
Anti-FSTL1 Antibody (6R820) 是一种 Rabbit 抗体，靶向 FSTL1。Anti-FSTL1 Antibody (6R820) 可用于 ICC/IF。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FSTL1 Antibody (6R820) is a Rabbit antibody targeting FSTL1. Anti-FSTL1 Antibody (6R820) can be used in ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6R820 |
| 交叉反应 | Human |
| 验证活性 | Confocal immunofluorescence staining of Human FSTL1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human FSTL1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 594-conjugated goat Anti-rabbit IgG secondary antibody (red), countstained with Alexa Fluor® 488-conjugated anti-tubulin antibody (green) and DAPI (blue).Positive staining was localized to cytoplasm. |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FSTL1 (rh FSTL1; TMPY-01106; NP_009016.1; Met1-Ile308). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FSTL1 protein (TMPY-01106) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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