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Anti-human CD16 Antibody (6K437)

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货号 TMAB-07388

Anti-human CD16 Antibody (6K437) 是一种 Mouse 抗体，靶向 human CD16。Anti-human CD16 Antibody (6K437) 可用于 FCM。

Anti-human CD16 Antibody (6K437)

Anti-human CD16 Antibody (6K437)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07388

Anti-human CD16 Antibody (6K437) 是一种 Mouse 抗体，靶向 human CD16。Anti-human CD16 Antibody (6K437) 可用于 FCM。

规格价格库存数量
100 μg
¥ 1,860
5日内发货
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产品介绍

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产品描述
Anti-human CD16 Antibody (6K437) is a Mouse antibody targeting human CD16. Anti-human CD16 Antibody (6K437) can be used in FCM.
Ig Type
Mouse IgG1, k
克隆号
6K437
反应种属
Human
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell membrane. Secreted. Exists also as a soluble receptor.
组织特异性Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4).
研究背景This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
抗原信息
基因名称
FCGR3A
基因ID
2214
蛋白名称
Low affinity immunoglobulin gamma Fc region receptor III-A
功能
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
化学信息
分子量Theoretical: 27 kDa. Actual: 50-65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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