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Anti-DPP2 Antibody (9E167) 是一种 Rabbit 抗体,靶向 DPP2。Anti-DPP2 Antibody (9E167) 可用于 ELISA。
Anti-DPP2 Antibody (9E167) 是一种 Rabbit 抗体,靶向 DPP2。Anti-DPP2 Antibody (9E167) 可用于 ELISA。
产品描述 | Anti-DPP2 Antibody (9E167) is a Rabbit antibody targeting DPP2. Anti-DPP2 Antibody (9E167) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9E167 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse DPP7 / DPPII / DPP2 (rM DPP7 / DPPII / DPP2; TMPY-02737; Q9ET221; Met1-Arg506). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse DPP7 / DPPII / DPP2 Protein (TMPY-02737) |
抗原种属 | Mouse |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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