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顶部产品介绍化学信息储存和溶解信息计算器技术支持

ACVR2A Protein, Human, Recombinant (hFc)

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货号 TMPY-00659

别名 ACVR2, ACTRII, activin A receptor, type IIA

ACVR2A Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P27037-1(Human)/G7PKJ4(Cynomolgus).

ACVR2A Protein, Human, Recombinant (hFc)
其他形式的 “ACVR2A Protein, Human, Recombinant (hFc)”:
ACVR2A Protein, Human, Recombinant (hFc & His)
ACVR2A Protein, Mouse, Recombinant (His)
ACVR2A Protein, Mouse, Recombinant (His & hFc)
ACVR2A Protein, Human, Recombinant (His)

ACVR2A Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPY-00659 别名 ACVR2, ACTRII, activin A receptor, type IIA

ACVR2A Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P27037-1(Human)/G7PKJ4(Cynomolgus).

规格价格库存数量
5 μg
¥ 385
6-8日内发货
10 μg
¥ 623
6-8日内发货
20 μg
¥ 987
5日内发货
50 μg
¥ 1,980
5日内发货
100 μg
¥ 3,380
5日内发货
200 μg
¥ 6,670
5日内发货
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产品介绍

生物活性
产品描述
ACVR2A Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P27037-1(Human)/G7PKJ4(Cynomolgus).
生物活性
Immobilized Human Activin A, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, hFc Tag with the EC50 of 1.6ng/ml determined by ELISA (QC Test).
Immobilized Human/Mouse/Rat GDF-8, No Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIA, hFc Tag with the EC50 of 56.9ng/ml determined by ELISA.
Human Activin RIIA, hFc Tag captured on CM5 Chip via Protein A can bind Human/Mouse/Rat GDF-8, No Tag with an affinity constant of 0.13 nM as determined in SPR assay (Biacore T200).
研究背景
Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.
种属
Human,Cynomolgus
表达系统
HEK293 Cells
标签C-hFc
蛋白编号P27037-1(Human)/G7PKJ4(Cynomolgus)
蛋白构建Ala20-Pro135
蛋白纯度
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名ACVR2, ACTRII, activin A receptor, type IIA
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量39.35 kDa (Predicted); 55-65 kDa (Reducing conditions due to glycosylation)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

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关键词

ACVR-2ACVR 2
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