规格

价格

库存

数量

1 mg

¥ 912

现货

5 mg

¥ 1,860

现货

10 mg

¥ 2,730

现货

25 mg

¥ 4,350

现货

50 mg

¥ 5,870

现货

100 mg

¥ 7,920

现货

1 mL x 10 mM (in DMSO)

¥ 4,130

现货

生物活性

产品描述	Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons.
体内活性	Apelin-12 acetate 显著改善了缺血再灌注损伤小鼠的神经行为评分，减轻了脑水肿和神经元损伤。Apelin-12 acetate 抑制了小鼠缺血半暗带神经细胞的形态变化和凋亡。Apelin-12 acetate 下调Bax和caspase-3的表达，抑制caspase-3的活性，并上调抗凋亡蛋白Bcl-2的表达[2]。
别名	Apelin-12 acetate (229961-08-4 Free base)

化学信息

分子量	1482.75
分子式	C₆₆H₁₀₇N₂₁O₁₆S
Smiles	CC(O)=O.O=C([C@H]1N(CCC1)C([C@@H](N)CCCNC(N)=N)=O)N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(NCC(N2[C@H](C(N[C@H](C(N3CCC[C@H]3C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)CCSC)=O)CCC2)=O)=O)CCCCN)=O)CC5=CN=CN5)=O)=O)=O)CCCNC(N)=N
颜色	White
物理性状	Solid
Sequence	H2N-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-COOH
Sequence Short	H2N-RPRLSHKGPMPF-OH

储存&溶解度

存储

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 22.5 mg/mL (15.17 mM), Sonication is recommended.