购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PHD2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10261

Anti-PHD2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PHD2。Anti-PHD2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-PHD2 Polyclonal Antibody

Anti-PHD2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10261

Anti-PHD2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PHD2。Anti-PHD2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-PHD2 Polyclonal Antibody is a Rabbit antibody targeting PHD2. Anti-PHD2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Pig,Cow,Rabbit)
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性According to PubMed:11056053, widely expressed with highest levels in skeletal muscle and heart, moderate levels in pancreas, brain (dopaminergic neurons of adult and fetal substantia nigra) and kidney, and lower levels in lung and liver. According to PubMed:12351678 widely expressed with highest levels in brain, kidney and adrenal gland. Expressed in cardiac myocytes, aortic endothelial cells and coronary artery smooth muscle. According to PubMed:12788921; expressed in adult and fetal heart, brain, liver, lung, skeletal muscle and kidney. Also expressed in placenta. Highest levels in adult heart, brain, lung and liver and fetal brain, heart spleen and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PHD2 protein catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. In the presence of oxygen, PHD2 converts specific prolyl residues in HIF alpha to hydroxyproline, leading to HIF alpha proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF levels are stable. This results in increased angiogenesis as HIF1 alpha regulates the expression of many angiogenesis-related genes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PHD2
抗原种属
Human
基因名称
EGLN1
基因ID
54583
蛋白名称
Egl nine homolog 1
Uniprot ID
Q9GZT9
化学信息
分子量Theoretical: 47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-PHD2 Polyclonal Antibody | purchase Anti-PHD2 Polyclonal Antibody | Anti-PHD2 Polyclonal Antibody cost | order Anti-PHD2 Polyclonal Antibody | Anti-PHD2 Polyclonal Antibody molecular weight