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Anti-SLC2A6 Polyclonal Antibody

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货号 TMAB-01717

别名 Solute carrier family 2, facilitated glucose transporter member 6, SLC2A6, RP23-449M10.2, HSA011372, GTR6, GLUT-6, Glut6, Glucose transporter type 6, Glucose Transporter GLUT6, F630103L12Rik, A330096C23

Anti-SLC2A6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SLC2A6。Anti-SLC2A6 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-SLC2A6 Polyclonal Antibody

Anti-SLC2A6 Polyclonal Antibody

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货号 TMAB-01717 别名 Solute carrier family 2, facilitated glucose transporter member 6, SLC2A6, RP23-449M10.2, HSA011372, GTR6, GLUT-6, Glut6, Glucose transporter type 6, Glucose Transporter GLUT6, F630103L12Rik, A330096C23

Anti-SLC2A6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SLC2A6。Anti-SLC2A6 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-SLC2A6 Polyclonal Antibody is a Rabbit antibody targeting SLC2A6. Anti-SLC2A6 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
别名Solute carrier family 2, facilitated glucose transporter member 6, SLC2A6, RP23-449M10.2, HSA011372, GTR6, GLUT-6, Glut6, Glucose transporter type 6, Glucose Transporter GLUT6, F630103L12Rik, A330096C23
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
验证活性
1. Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-GLUT6 Polyclonal Antibody, Unconjugated (TMAB-01717) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Tissue/cell: rat spleen tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-GLUT6 Polyclonal Antibody, Unconjugated (TMAB-01717) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
3. Sample:
Brain (Mouse) Lysate at 40 μg
Primary: Anti-GLUT6/GLUT9 (TMAB-01717) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
4. Sample:
Heart (Mouse) Lysate at 40 μg
Primary: Anti-GLUT6/GLUT9 (TMAB-01717) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. The dileucine internalization motif is critical for intracellular sequestration.
组织特异性Highly expressed in brain, spleen and peripheral blood leukocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The oxidation of glucose functions as the dominant source of metabolic energy for mammals. The plasma membrane is impermeable to glucose, so the cellular uptake of this important nutrient is achieved by facultative hexose transproters (Gluts). Gluts are integral membrane proteins that transport glucose and related hexoses. Glucose binds to a Glut on one side of the membrane which provokes a conformational change causing it to release glucose to the other side. Members of the Glut family may enhance the metabolic activity of tumor cells. Glut6 is part of the third out of three classes of Gluts. Glut6 is mainly expressed in the brain, spleen and peripheral leukocytes. It appears to be regulated by subcellular redistribution, because it is targeted to intracellular compartments by di-leucine motifs, recycling itself in a Dynamin-dependent manner.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GLUT6
抗原种属
Human
基因名称
SLC2A6
基因ID
蛋白名称
Solute carrier family 2, facilitated glucose transporter member 6
Uniprot ID
研究领域
Cancer,Channels
功能
Facilitative glucose transporter; binds cytochalasin B with low affinity.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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