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Anti-Proteasome 20S alpha 1 Polyclonal Antibody

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货号 TMAB-11800

Anti-Proteasome 20S alpha 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Proteasome 20S alpha 1。Anti-Proteasome 20S alpha 1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Proteasome 20S alpha 1 Polyclonal Antibody

Anti-Proteasome 20S alpha 1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11800

Anti-Proteasome 20S alpha 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Proteasome 20S alpha 1。Anti-Proteasome 20S alpha 1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Proteasome 20S alpha 1 Polyclonal Antibody is a Rabbit antibody targeting Proteasome 20S alpha 1. Anti-Proteasome 20S alpha 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Induced in breast cancer tissue (at protein level). Up-regulated in liver tumor tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Proteasome 20S alpha
抗原种属
Human
基因名称
PSMA1
基因ID
5682
蛋白名称
Proteasome subunit alpha type-1
Uniprot ID
P25786
功能
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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