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Anti-PTGER2 Polyclonal Antibody

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Anti-PTGER2 Polyclonal Antibody
产品编号 TMAB-01592

Anti-PTGER2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTGER2。Anti-PTGER2 Polyclonal Antibody 可用于 WB。

Anti-PTGER2 Polyclonal Antibody

Anti-PTGER2 Polyclonal Antibody

Rating icon 还可以
Anti-PTGER2 Polyclonal Antibody
产品编号 TMAB-01592

Anti-PTGER2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTGER2。Anti-PTGER2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-PTGER2 Polyclonal Antibody is a Rabbit antibody targeting PTGER2. Anti-PTGER2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat,Sheep (predicted:Dog,Pig,Cow,Rabbit)
验证活性
Sample:
Lane 1: Mouse Spleen tissue lysates
Lane 2: Mouse Urinary bladder tissue lysates
Lane 3: Mouse Placenta tissue lysates
Lane 4: Rat Urinary bladder tissue lysates
Lane 5: Rat Placenta tissue lysates
Lane 6: Human MCF-7 cell lysates
Lane 7: Human JAR cell lysates
Lane 8: Human HL60 cell lysates
Primary: Anti-PTGER2 (TMAB-01592) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 48 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Prostaglandins are produced by the metabolism of arachidonic acid. Prostaglandin E2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues is mediated through binding to the Prostaglandin E2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. Prostaglandin E2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo Prostaglandin E2 induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Prostaglandin E Receptor EP2
抗原种属
Human
基因ID
Uniprot ID
研究领域
Lipid metabolism,Prostaglandins
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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