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Anti-PTGER2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTGER2。Anti-PTGER2 Polyclonal Antibody 可用于 WB。
Anti-PTGER2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PTGER2。Anti-PTGER2 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,970 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-PTGER2 Polyclonal Antibody is a Rabbit antibody targeting PTGER2. Anti-PTGER2 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat,Sheep (predicted:Dog,Pig,Cow,Rabbit) |
验证活性 | Sample: Lane 1: Mouse Spleen tissue lysates Lane 2: Mouse Urinary bladder tissue lysates Lane 3: Mouse Placenta tissue lysates Lane 4: Rat Urinary bladder tissue lysates Lane 5: Rat Placenta tissue lysates Lane 6: Human MCF-7 cell lysates Lane 7: Human JAR cell lysates Lane 8: Human HL60 cell lysates Primary: Anti-PTGER2 (TMAB-01592) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 48 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Prostaglandins are produced by the metabolism of arachidonic acid. Prostaglandin E2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues is mediated through binding to the Prostaglandin E2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. Prostaglandin E2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo Prostaglandin E2 induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle. |
免疫原 | KLH conjugated synthetic peptide: human Prostaglandin E Receptor EP2 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Lipid metabolism,Prostaglandins |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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