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Anti-CX3CL1/Fractalkine Polyclonal Antibody

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货号 TMAB-00493

别名 Small-inducible cytokine D1, SCYD1, NTT, Neurotactin, Fractalkine, FKN, CX3CL1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine

Anti-CX3CL1/Fractalkine Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CX3CL1/Fractalkine。Anti-CX3CL1/Fractalkine Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-CX3CL1/Fractalkine Polyclonal Antibody

Anti-CX3CL1/Fractalkine Polyclonal Antibody

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货号 TMAB-00493 别名 Small-inducible cytokine D1, SCYD1, NTT, Neurotactin, Fractalkine, FKN, CX3CL1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine

Anti-CX3CL1/Fractalkine Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CX3CL1/Fractalkine。Anti-CX3CL1/Fractalkine Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CX3CL1/Fractalkine Polyclonal Antibody is a Rabbit antibody targeting CX3CL1/Fractalkine. Anti-CX3CL1/Fractalkine Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名Small-inducible cytokine D1, SCYD1, NTT, Neurotactin, Fractalkine, FKN, CX3CL1, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
验证活性
Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-CX3CL1 Polyclonal Antibody, Unconjugated (TMAB-00493) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
verifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted.
组织特异性Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CX3CL1
抗原种属
Human
基因名称
CX3CL1
基因ID
6376
蛋白名称
Fractalkine
Uniprot ID
P78423
研究领域
Macrophage / Inflamm.,Delta Chemokines (CXC3),Chemokines
功能
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

SCYD 1CX3CL 1
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