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Anti-RNF169 Polyclonal Antibody

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货号 TMAB-12305

Anti-RNF169 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF169。Anti-RNF169 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-RNF169 Polyclonal Antibody

Anti-RNF169 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12305

Anti-RNF169 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 RNF169。Anti-RNF169 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-RNF169 Polyclonal Antibody is a Rabbit antibody targeting RNF169. Anti-RNF169 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleoplasm. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RNF169 contains 1 RING type zinc finger. The exact functions of RNF169 remain unknown.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RNF169
抗原种属
Human
基因名称
RNF169
基因ID
蛋白名称
E3 ubiquitin-protein ligase RNF169
Uniprot ID
功能
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.
化学信息
分子量Theoretical: 77 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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