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Anti-HGFR/c-Met Antibody-PE (6L502)
还可以产品编号 TMAY-01069P
Anti-HGFR/c-Met Antibody-PE (6L502) 是一种 PE-conjugated Rabbit 抗体，靶向 HGFR/c-Met。Anti-HGFR/c-Met Antibody-PE (6L502) 可用于 FCM。
Anti-HGFR/c-Met Antibody-PE (6L502)
Anti-HGFR/c-Met Antibody-PE (6L502)
还可以产品编号 TMAY-01069P
Anti-HGFR/c-Met Antibody-PE (6L502) 是一种 PE-conjugated Rabbit 抗体，靶向 HGFR/c-Met。Anti-HGFR/c-Met Antibody-PE (6L502) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-HGFR/c-Met Antibody-PE (6L502) is a PE-conjugated Rabbit antibody targeting HGFR/c-Met. Anti-HGFR/c-Met Antibody-PE (6L502) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6L502 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-human C-Met (HGF R) reactivity on HepG2 cells analyzed by flow cytometry. The Clone 6L502 and 4V580 monoclonal antibodies are not cross-blocking. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human HGFR / c-MET (rh HGFR / c-MET; TMPY-00718; NP_000236.2; Met 1-Thr 932) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human HGFR / c-MET protein (TMPY-00718) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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