购物车

您的购物车当前为空

7-Methylxanthine

Name: 7-Methylxanthine
Brand: TargetMol
SKU: T0543
Price: 145 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: Heteroxanthine, Heteroxanthin, 7-甲基黄嘌呤

货号 T0543Cas号 552-62-5 一键复制产品信息纯度: 99.81%

很棒

7-Methylxanthine 是一种黄嘌呤的甲基衍生物，是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。

7-Methylxanthine

一键复制产品信息

很棒

纯度: 99.81%

货号 T0543Cas号 552-62-5

别名 Heteroxanthine, Heteroxanthin, 7-甲基黄嘌呤

7-Methylxanthine 是一种黄嘌呤的甲基衍生物，是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。

规格	价格	库存
5 mg	¥ 145	现货
10 mg	¥ 198	现货
25 mg	¥ 297	现货
50 mg	¥ 445	现货
100 mg	¥ 733	现货
1 mL x 10 mM (in DMSO)	¥ 329	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.81%

颜色: 白色

资源下载: COA HNMR LCMS产品操作手册

产品介绍

7-Methylxanthine AI Summary

7-Methylxanthine demonstrates binding affinity at the Adenosine A1 receptor in rat brain cortical membranes with a Ki of 33,000.0 nM, and at the Adenosine A2 receptor in rat striatal membranes with a Ki of 59,000.0 nM. It also exhibits bioactivity as a GDA inhibitor with a Ki of 5550.0 nM determined through a colorimetric assay. Antiviral activity against SARS-CoV-2 has been observed, including inhibition of virus-induced cytotoxicity in Caco-2 cells at 10 µM, measured by high content imaging, resulting in an inhibition percentage of -5.77%. The compound also showed 10.81% inhibition of SARS-CoV-2 3CL-Pro protease at 20 µM using a FRET assay. Additionally, inhibition of cytotoxicity was noted in VERO-6 cells at 10 µM, although the IC50 value exceeded 20,000.0 nM, suggesting limited potency. 7-Methylxanthine's inhibition of human HDAC6 was minimal, showing 9.47% inhibition with a commercial peptide substrate and -2.27% with a custom peptide substrate..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	7-Methylxanthine is a methyl derivative of xanthine, the purine component of human urinary calculi.7-Methylxanthine has an affinity for adenosine receptors.7-Methylxanthine is a methyl derivative of xanthine, the purine component of human urinary calculi.7-Methylxanthine has an affinity for adenosine receptors.
别名	Heteroxanthine, Heteroxanthin, 7-甲基黄嘌呤

化学信息

分子量	166.14
分子式	C₆H₆N₄O₂
CAS No.	552-62-5
Smiles	Cn1cnc2[nH]c(=O)[nH]c(=O)c12
密度	1.83 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

H2O: < 1 mg/mL (insoluble)

DMSO: 3.8 mg/mL (22.87 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0190 mL	30.0951 mL	60.1902 mL	300.9510 mL
5 mM	1.2038 mL	6.0190 mL	12.0380 mL	60.1902 mL
10 mM	0.6019 mL	3.0095 mL	6.0190 mL	30.0951 mL
20 mM	0.3010 mL	1.5048 mL	3.0095 mL	15.0476 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。