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Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2
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还可以产品编号 TMAB-10933
Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-MAP3K8 (Thr290)。Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2
Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-10933
Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-MAP3K8 (Thr290)。Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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| 产品描述 | Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-MAP3K8 (Thr290). Anti-Phospho-MAP3K8 (Thr290) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 交叉反应 | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expressed in several normal tissues and human tumor-derived cell lines. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human MAP3K8/Tpl2 around the phosphorylation site of Thr290 |
| 抗原种属 | Human |
| 基因名称 | MAP3K8 |
| 基因ID | |
| 蛋白名称 | Mitogen-activated protein kinase kinase kinase 8 |
| Uniprot ID | |
| 功能 | Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein. |
| 分子量 | Theoretical: 53 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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