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Anti-Diazepam Binding Inhibitor Polyclonal Antibody

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货号 TMAB-05143

Anti-Diazepam Binding Inhibitor Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Diazepam Binding Inhibitor。Anti-Diazepam Binding Inhibitor Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Diazepam Binding Inhibitor Polyclonal Antibody

Anti-Diazepam Binding Inhibitor Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05143

Anti-Diazepam Binding Inhibitor Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Diazepam Binding Inhibitor。Anti-Diazepam Binding Inhibitor Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Diazepam Binding Inhibitor Polyclonal Antibody is a Rabbit antibody targeting Diazepam Binding Inhibitor. Anti-Diazepam Binding Inhibitor Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum. Golgi apparatus.Note=Golgi localization is dependent on ligand binding.
组织特异性Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human ACBD/Diazepam Binding Inhibitor
抗原种属
Human
基因名称
DBI
基因ID
1622
蛋白名称
Acyl-CoA-binding protein
Uniprot ID
P07108
功能
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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