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Anti-SLAM/CD150 Antibody (7T861)
还可以产品编号 TMAY-01243
Anti-SLAM/CD150 Antibody (7T861) 是一种 Mouse 抗体，靶向 SLAM/CD150。Anti-SLAM/CD150 Antibody (7T861) 可用于 ELISA。
Anti-SLAM/CD150 Antibody (7T861)
Anti-SLAM/CD150 Antibody (7T861)
还可以产品编号 TMAY-01243
Anti-SLAM/CD150 Antibody (7T861) 是一种 Mouse 抗体，靶向 SLAM/CD150。Anti-SLAM/CD150 Antibody (7T861) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SLAM/CD150 Antibody (7T861) is a Mouse antibody targeting SLAM/CD150. Anti-SLAM/CD150 Antibody (7T861) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7T861 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SLAMF1 / CD150 (rh SLAMF1; TMPY-01016; NP_003028.1; Met 1-Pro 258). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CD150 protein (TMPY-01016) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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