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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Emerin Antibody (2U299)

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货号 TMAB-05552

Anti-Emerin Antibody (2U299) 是一种 Rabbit 抗体，靶向 Emerin。Anti-Emerin Antibody (2U299) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Emerin Antibody (2U299)

Anti-Emerin Antibody (2U299)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05552

Anti-Emerin Antibody (2U299) 是一种 Rabbit 抗体，靶向 Emerin。Anti-Emerin Antibody (2U299) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Emerin Antibody (2U299) is a Rabbit antibody targeting Emerin. Anti-Emerin Antibody (2U299) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
2U299
反应种属
Human,Mouse (predicted:Rat)
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus inner membrane; Single-pass membrane protein; Nucleoplasmic side. Nucleus outer membrane. Note=Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus.
组织特异性Skeletal muscle, heart, colon, testis, ovary and pancreas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Emerin may regulate gene expression through binding to other transcriptional regulators. Emerin binds to β-catenin and inhibits its nuclear accumulation. Recent studies demonstrate that Emerin is required for HIV-1 infectivity.
抗原信息
免疫原
A synthesized peptide: human Emerin
抗原种属
Human
基因名称
EMD
基因ID
2010
蛋白名称
Emerin
Uniprot ID
P50402
功能
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
化学信息
分子量Theoretical: 29 kDa. Actual: 29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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