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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RRM2 Polyclonal Antibody

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货号 TMAB-01636

别名 RRM2, RR2, Ribonucleotide Reductase Small Subunit, Ribonucleotide Reductase Small Chain, Ribonucleoside-Diphosphate Reductase Subunit M2

Anti-RRM2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RRM2。Anti-RRM2 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB。

Anti-RRM2 Polyclonal Antibody

Anti-RRM2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01636 别名 RRM2, RR2, Ribonucleotide Reductase Small Subunit, Ribonucleotide Reductase Small Chain, Ribonucleoside-Diphosphate Reductase Subunit M2

Anti-RRM2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RRM2。Anti-RRM2 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-RRM2 Polyclonal Antibody is a Rabbit antibody targeting RRM2. Anti-RRM2 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
别名RRM2, RR2, Ribonucleotide Reductase Small Subunit, Ribonucleotide Reductase Small Chain, Ribonucleoside-Diphosphate Reductase Subunit M2
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用ELISAICC/IFIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Ribonucleotide reductase is essential for the production and maintenance of the level of deoxyribonucleoside triphosphates (dNTPs) required for DNA synthesis. It is an enzymatic complex consisting of two nonidentical subunits, R1 and R2, which are inactive separately. R2, the smaller subunit, is localized to the cytoplasm. R2 is the limiting factor of the catalytic activity of the ribonucleotide reductase enzymatic complex. R2 expression is strictly correlated to the S-phase of the cell cycle, whereas R1 remains constant throughout all phases of the cell cycle. While R2 seems to be involved solely in the maintenance of dNTPs for DNA replication, a similar protein, p53R2, has been shown to be responsible for the production of dNTPs in response to DNA damage. Function : Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RRM2
抗原种属
Human
基因名称
RRM2
基因ID
6241
蛋白名称
Ribonucleoside-diphosphate reductase subunit M2
Uniprot ID
P31350
研究领域
p53 pathway,p53,DNA Synthesis,Nucleotide metabolism
功能
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

RRM-2RRM 2RR-2RR 2
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