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Fibromodulin Protein, Human, Recombinant (hFc)

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SPR兼容缓冲液
货号 TMPY-04801

别名 SLRR2E, FM, fibromodulin

Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therapy for repressing tumor angiogenesis.

Fibromodulin Protein, Human, Recombinant (hFc)
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Fibromodulin Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPY-04801 别名 SLRR2E, FM, fibromodulin

Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therapy for repressing tumor angiogenesis.

规格价格库存数量
5 μg
¥ 493
现货
10 μg
¥ 790
现货
20 μg
¥ 1,330
5日内发货
50 μg
¥ 2,580
5日内发货
100 μg
¥ 5,170
5日内发货
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选择批次:
纯度: > 90 % as determined by SDS-PAGE.
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therapy for repressing tumor angiogenesis.
生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FMOD of cancer cells may promote tumor angiogenesis of SCLC by upregulating the expression of angiogenic factors that act in concert to facilitate the angiogenic phenotype of endothelial cells as a proangiogenic factor. Therefore, silencing FMOD may be a potentially clinical therapy for repressing tumor angiogenesis.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号Q06828
蛋白构建A DNA sequence encoding the human FMOD (NP_002014.2) (Met1-Ile376) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 19
蛋白纯度
> 90 % as determined by SDS-PAGE.
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名SLRR2E, FM, fibromodulin
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量68.2 kDa (predicted)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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