规格

价格

库存

数量

1 mg

¥ 783

现货

5 mg

¥ 2,000

现货

10 mg

¥ 2,800

现货

25 mg

¥ 4,160

现货

50 mg

¥ 5,580

现货

100 mg

¥ 7,420

现货

200 mg

¥ 10,000

现货

1 mL x 10 mM (in DMSO)

¥ 553

现货

生物活性

产品描述	FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency. Additionally, FSCPX can effectively decrease the interstitial adenosine level in the guinea pig atrium, thereby modifying the effect of NBTI, a nucleoside transport inhibitor.
靶点活性	DDT1 MF2 cells:11.8±3.2 nM
体外活性	FSCPX（2-20 μM；48小时）在不影响HSP70 mRNA或蛋白表达的情况下，逆转了A1AR过表达的LLC-PK1细胞中HSP27 mRNA和蛋白的上调。FSCPX（20 μM；48小时）减弱了A1AR过表达的LLC-PK1细胞对坏死和凋亡的保护作用。[3]

化学信息

分子量	506.55
分子式	C₂₃H₂₇FN₄O₆S
CAS No.	156547-56-7
Smiles	CCCn1c(=O)n(CCCOC(=O)c2ccc(cc2)S(F)(=O)=O)c2[nH]c(nc2c1=O)C1CCCC1

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 45 mg/mL (88.84 mM), Sonication and heating to 60℃ are recommended.

体内实验配方

10% DMSO+90% Corn Oil: 2 mg/mL (3.95 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO