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顶部产品介绍化学信息储存和溶解信息计算器

Sphingosine (d20:1)

Synonyms: Sphingosine (d20:1)
货号 T37954Cas号 6918-49-6 一键复制产品信息
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Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which are predominantly composed of C-18 sphingosine, only central nervous system (CNS) gangliosides contain significant amounts of sphingosine. The concentration of sphingosine within mammalian brain gangliosides apparently increases with developmental maturation. Furthermore, the ratio of C-18 to C-20 sphingosine in the brain is thought to be related to some nervous system degeneration processes.

Sphingosine (d20:1)

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货号 T37954Cas号 6918-49-6

别名 Sphingosine (d20:1)

Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which are predominantly composed of C-18 sphingosine, only central nervous system (CNS) gangliosides contain significant amounts of sphingosine. The concentration of sphingosine within mammalian brain gangliosides apparently increases with developmental maturation. Furthermore, the ratio of C-18 to C-20 sphingosine in the brain is thought to be related to some nervous system degeneration processes.

Sphingosine (d20:1)
其他形式的 “Sphingosine (d20:1)”:
Sphingosine (d14:1)T3826224558-60-9
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规格价格库存数量
500 μg
¥ 836
35日内发货
1 mg
¥ 1,560
35日内发货
5 mg
¥ 4,300
35日内发货
10 mg
¥ 4,780
35日内发货
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产品介绍

生物活性
产品描述
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which are predominantly composed of C-18 sphingosine, only central nervous system (CNS) gangliosides contain significant amounts of sphingosine. The concentration of sphingosine within mammalian brain gangliosides apparently increases with developmental maturation. Furthermore, the ratio of C-18 to C-20 sphingosine in the brain is thought to be related to some nervous system degeneration processes.
别名Sphingosine (d20:1)
化学信息
分子量327.55
分子式C20H41NO2
CAS No.6918-49-6
SmilesCCCCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)CO
密度no data available
储存&溶解度
存储
溶解度信息
Ethanol: Miscible
DMSO: 2.00 mg/mL (6.11 mM), Sonication is recommended.
DMF: 10.00 mg/mL (30.53 mM), Sonication is recommended.
溶液配制表
DMSO/DMF
1mg5mg10mg50mg
1 mM3.0530 mL15.2648 mL30.5297 mL152.6485 mL
5 mM0.6106 mL3.0530 mL6.1059 mL30.5297 mL
DMF
1mg5mg10mg50mg
10 mM0.3053 mL1.5265 mL3.0530 mL15.2648 mL
20 mM0.1526 mL0.7632 mL1.5265 mL7.6324 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

Sphingosine (d-20:1)Sphingosined20:1
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