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Anti-PNPLA2 Antibody (8N289)
还可以产品编号 TMAH-00993
Anti-PNPLA2 Antibody (8N289) 是一种抗体，靶向 PNPLA2。Anti-PNPLA2 Antibody (8N289) 可用于 ELISA, FC。
Anti-PNPLA2 Antibody (8N289)
Anti-PNPLA2 Antibody (8N289)
还可以产品编号 TMAH-00993
Anti-PNPLA2 Antibody (8N289) 是一种抗体，靶向 PNPLA2。Anti-PNPLA2 Antibody (8N289) 可用于 ELISA, FC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PNPLA2 Antibody (8N289) is an antibody targeting PNPLA2. Anti-PNPLA2 Antibody (8N289) can be used in ELISA, FC. |
| Ig Type | Rabbit IgG |
| 克隆号 | 8N289 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing HepG2 cells stained with TMAH-00993 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | ELISA, FC |
| 推荐剂量 | FC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Lipid droplet. Cell membrane; Single-pass type II membrane protein. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone. Also has acylglycerol transacylase activity. Acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human PNPLA2 |
| 抗原种属 | Human |
| 基因ID | 57104 |
| Uniprot ID | |
| 研究领域 | Cancer, Cardiovascular, Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
关键词
TTS2.2TTS2TTS 2.2TTS 2Transport-secretion protein 2 (TTS2)PNPLA2PNPLA 2Pigment epithelium-derived factor receptor (PEDF-R)PEDF-RPEDFRPatatin-like phospholipase domain-containing protein 2iPLA2-ζiPLA2ζiPLA2-zetaiPLA2zetaDesnutrinCalcium-independent phospholipase A2-ζ (iPLA2-ζ)Calcium-independent phospholipase A2-zeta (iPLA2-zeta)ATGLAdipose triglyceride lipase
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