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Anti-PNPLA2 Antibody (8N289)
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产品编号 TMAH-00993
Anti-PNPLA2 Antibody (8N289) 是一种抗体，靶向 PNPLA2。Anti-PNPLA2 Antibody (8N289) 可用于 ELISA, FCM。
Anti-PNPLA2 Antibody (8N289)
Anti-PNPLA2 Antibody (8N289)
还可以产品编号 TMAH-00993
Anti-PNPLA2 Antibody (8N289) 是一种抗体，靶向 PNPLA2。Anti-PNPLA2 Antibody (8N289) 可用于 ELISA, FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PNPLA2 Antibody (8N289) is an antibody targeting PNPLA2. Anti-PNPLA2 Antibody (8N289) can be used in ELISA, FCM. |
| Ig Type | Rabbit IgG |
| 克隆号 | 8N289 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing HepG2 cells stained with TMAH-00993 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | |
| 推荐剂量 | FCM:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Lipid droplet. Cell membrane; Single-pass type II membrane protein. |
| 组织特异性 | Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner seg |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone. Also has acylglycerol transacylase activity. Acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human PNPLA2 |
| 抗原种属 | Human |
| 基因名称 | PNPLA2 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cancer, Cardiovascular, Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
关键词
TTS2.2TTS2TTS 2.2TTS 2Transport-secretion protein 2 (TTS2)PNPLA2PNPLA 2Pigment epithelium-derived factor receptor (PEDF-R)PEDF-RPEDFRPatatin-like phospholipase domain-containing protein 2iPLA2-ζiPLA2ζiPLA2-zetaiPLA2zetaDesnutrinCalcium-independent phospholipase A2-ζ (iPLA2-ζ)Calcium-independent phospholipase A2-zeta (iPLA2-zeta)ATGLAdipose triglyceride lipase
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