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Anti-IL-10 Polyclonal Antibody 2

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货号 TMAB-00937

别名 白介素, interleukin 10, Il-10, CSIF

Anti-IL-10 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 IL-10。Anti-IL-10 Polyclonal Antibody 2 可用于 WB。

Anti-IL-10 Polyclonal Antibody 2

Anti-IL-10 Polyclonal Antibody 2

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货号 TMAB-00937 别名 白介素, interleukin 10, Il-10, CSIF

Anti-IL-10 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 IL-10。Anti-IL-10 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-10 Polyclonal Antibody 2 is a Rabbit antibody targeting IL-10. Anti-IL-10 Polyclonal Antibody 2 can be used in WB.
别名白介素, interleukin 10, Il-10, CSIF
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
1. Sample:
Plasma (Rat) at 40 μg
Plasma (Rat) at 40 μg
Primary: Anti-IL-10 (TMAB-00937) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 20 kDa
2. Sample:
Raw264.7 (Mouse) Lysate at 30 μg
Primary: Anti-IL-10 (TMAB-00937) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 20 kDa
3. Sample:
Lane 1: Recombinant human IL-10 protein, His (HEK293)
Primary: Anti-IL-10 (TMAB-00937) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 17 kDa
verifiedActivityverifiedActivityverifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]
抗原信息
免疫原
KLH conjugated synthetic peptide: human IL-10
抗原种属
Human
基因名称
IL10
基因ID
3586
蛋白名称
Interleukin-10
Uniprot ID
P22301
研究领域
Interleukins,Regulatory T Cells,Interleukins
功能
IL-10 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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