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顶部生物活性储存和溶解信息计算器

Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 2

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产品编号 TMAC-00047

别名 p-C-ABL/ABL1 (Thr735), p-C-ABL/ABL1 (T735), C-ABL/ABL1 (p-Thr735), C-ABL/ABL1 (p-T735)

Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-C-ABL/ABL1 (Thr735)。Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 可用于 WB。

Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 2

Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 2

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产品编号 TMAC-00047 别名 p-C-ABL/ABL1 (Thr735), p-C-ABL/ABL1 (T735), C-ABL/ABL1 (p-Thr735), C-ABL/ABL1 (p-T735)

Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-C-ABL/ABL1 (Thr735)。Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-ABL/ABL1 (Thr735). Anti-Phospho-C-ABL/ABL1 (Thr735) Polyclonal Antibody can be used in WB.
别名p-C-ABL/ABL1 (Thr735), p-C-ABL/ABL1 (T735), C-ABL/ABL1 (p-Thr735), C-ABL/ABL1 (p-T735)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from COS cells treated with EGF using ABL1 (Phospho-Thr735) Antibody TMAC-00047.The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine735 (S-V-T(p)-L-P) derived from Human ABL1
抗原种属
human
Uniprot ID
P00519
化学信息
分子量Actual: 135 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pC-ABL/ABL1 (Thr735)pC-ABL/ABL1 (T735)C-ABL/ABL1 (pThr735)C-ABL/ABL1 (pT735)C-ABL/ABL1 (phospho-Thr735)C-ABL/ABL1 (phospho-T735)

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