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ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
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还可以货号 TMPJ-00386
别名 Metalloprotease MPROT15, Angiotensin-Converting Enzyme Homolog, Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, ACEH, ACE2
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
其他形式的 “ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated”:
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
一键复制产品信息 还可以货号 TMPJ-00386 别名 Metalloprotease MPROT15, Angiotensin-Converting Enzyme Homolog, Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, ACEH, ACE2
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 815 | 6-8日内发货 | |
| 10 μg | ¥ 1,350 | 6-8日内发货 | |
| 20 μg | ¥ 2,260 | 5日内发货 | |
| 50 μg | ¥ 3,980 | 5日内发货 | |
| 100 μg | ¥ 6,130 | 5日内发货 |
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| 产品描述 | Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-Avi-6xHis |
| 蛋白编号 | Q9BYF1 |
| 氨基酸序列 | Gln18-Ser740 |
| 蛋白构建 | Gln18-Ser740 |
| 蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC. |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 1 mM ZnCl<sub>2</sub>, 10% Glycerol, pH 7.4. |
| 别名 | Metalloprotease MPROT15, Angiotensin-Converting Enzyme Homolog, Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, ACEH, ACE2 |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 110-140 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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