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Anti-LIF Antibody (6B693) 是一种 Mouse 抗体,靶向 LIF。Anti-LIF Antibody (6B693) 可用于 ELISA。
Anti-LIF Antibody (6B693) 是一种 Mouse 抗体,靶向 LIF。Anti-LIF Antibody (6B693) 可用于 ELISA。
产品描述 | Anti-LIF Antibody (6B693) is a Mouse antibody targeting LIF. Anti-LIF Antibody (6B693) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 6B693 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Leukemia Inhibitory Factor/LIF (rh Leukemia Inhibitory Factor/LIF; TMPY-03532; P15018; Met1-Phe202). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone metabolism, cachexia, neural development, embryogenesis, and inflammation. LIF has potent proinflammatory properties, being the inducer of the acute phase protein synthesis and affecting cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that are capable to regulate the differentiation of embryonic stem cells, hematopoietic, and neuronal cells. LIF binds to the specific LIF receptor (LIFR-α) which forms a heterodimer with a specific subunit common to all members of that family of receptors, the GP130 signal-transducing subunit. This leads to the activation of the JAK/STAT and MAPK cascades. Due to its polyfunctional activities, LIF is involved in the pathogenic events and development of many diseases of various origins. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Leukemia Inhibitory Factor/LIF Protein (TMPY-03532) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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