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Anti-TIM-1/KIM-1/HAVCR1 Antibody (9S145) 是一种 Rabbit 抗体,靶向 TIM-1/KIM-1/HAVCR1。Anti-TIM-1/KIM-1/HAVCR1 Antibody (9S145) 可用于 ELISA,IHC-P。
Anti-TIM-1/KIM-1/HAVCR1 Antibody (9S145) 是一种 Rabbit 抗体,靶向 TIM-1/KIM-1/HAVCR1。Anti-TIM-1/KIM-1/HAVCR1 Antibody (9S145) 可用于 ELISA,IHC-P。
产品描述 | Anti-TIM-1/KIM-1/HAVCR1 Antibody (9S145) is a Rabbit antibody targeting TIM-1/KIM-1/HAVCR1. Anti-TIM-1/KIM-1/HAVCR1 Antibody (9S145) can be used in ELISA,IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9S145 |
交叉反应 | Canine |
验证活性 | Immunochemical staining of Canine KIM1 in canine kidney with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
应用 | ELISA,IHC-P |
推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:1000-1:4000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Canine HAVCR1 extracellular domain (rCanine TIMD-1 / HAVCR1; TMPY-01350; XP_854888.1; Tyr 21-Ser 160). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling. |
偶联 | Unconjugated |
免疫原 | Recombinant Canine HAVCR1 protein (TMPY-01350) |
抗原种属 | Canine |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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