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GPRC5D Protein-VLP, Cynomolgus, Recombinant

GPRC5D Protein-VLP, Cynomolgus, Recombinant

产品编号 TMPK-00528
别名: MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

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GPRC5D Protein-VLP, Cynomolgus, Recombinant
规格 价格/CNY 货期 数量
100 μg ¥ 10,300 5日内发货
500 μg ¥ 41,500 5日内发货
1 mg ¥ 69,200 5日内发货
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产品目录号及名称: GPRC5D Protein-VLP, Cynomolgus, Recombinant (TMPK-00528)
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生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Cynomolgus GPRC5D VLP (100μl/well) at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.91μg/ml determined by ELISA.
产品描述 Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
种属 Cynomolgus
表达系统 HEK293
蛋白编号 A0A2K5W6I7
别名 MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor
蛋白构建 Recombinant Cynomolgus GPRC5D Protein-VLP is expressed from HEK293. It contains Met1-Cys300.[Accession |A0A2K5W6I7]
蛋白纯度 > 95% as determined by HPLC
分子量 The target protein has a predicted MW of 35.10 kDa.
内毒素 Less than 1EU per μg by the LAL method.
缓冲液 Supplied as 0.22μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
存储

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

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Keywords

GPRC5D Protein-VLP, Cynomolgus, Recombinant MGC129713 MGC-129713 MGC 129714 MGC-129714 GPRC5D MGC129714 MGC 129713 orphan G-protein coupled receptor recombinant recombinant-proteins proteins protein

 

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