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Anti-Thyroid peroxidase Antibody (6A392)
还可以产品编号 TMAY-02534
Anti-Thyroid peroxidase Antibody (6A392) 是一种 Mouse 抗体，靶向 Thyroid peroxidase。Anti-Thyroid peroxidase Antibody (6A392) 可用于 IHC-P。
Anti-Thyroid peroxidase Antibody (6A392)
Anti-Thyroid peroxidase Antibody (6A392)
还可以产品编号 TMAY-02534
Anti-Thyroid peroxidase Antibody (6A392) 是一种 Mouse 抗体，靶向 Thyroid peroxidase。Anti-Thyroid peroxidase Antibody (6A392) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Thyroid peroxidase Antibody (6A392) is a Mouse antibody targeting Thyroid peroxidase. Anti-Thyroid peroxidase Antibody (6A392) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6A392 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human TPO in human thyroid gland with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Thyroid peroxidase / TPO (rh Thyroid peroxidase / TPO ; TMPY-02779; P07202-1; Met1-Arg846,257Ser/Ala,725Pro/Thr). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx 100 kDa molecular weight. Thyroid peroxidase is an enzyme expressed abundantly in the thyroid that liberates iodine for addition onto tyrosine residues on thyroglobulin for the production of thyroxine or triiodothyronine, thyroid hormones. Thyroid peroxidase plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin to form precursors of the thyroid hormones T4 and T3. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Thyroid peroxidase / TPO Protein (TMPY-02779) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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