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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NEK6 Antibody (1W434)

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货号 TMAB-09348

Anti-NEK6 Antibody (1W434) 是一种 Rabbit 抗体，靶向 NEK6。Anti-NEK6 Antibody (1W434) 可用于 WB,IP。

Anti-NEK6 Antibody (1W434)

Anti-NEK6 Antibody (1W434)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09348

Anti-NEK6 Antibody (1W434) 是一种 Rabbit 抗体，靶向 NEK6。Anti-NEK6 Antibody (1W434) 可用于 WB,IP。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-NEK6 Antibody (1W434) is a Rabbit antibody targeting NEK6. Anti-NEK6 Antibody (1W434) can be used in WB,IP.
Ig Type
IgG
克隆号
1W434
反应种属
Human,Rat (predicted:Mouse)
应用WBIP
推荐剂量
WB: 1:500-2000; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Nucleus speckle. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Co-localizes with APBB1 at the nuclear speckles. Co-localizes with PIN1 in the nucleus. Co-localizes with ATF4, CIR1, ARHGAP33, ANKRA2, CDC42, NEK9, RAD26L, RBBP6, RPS7, TRIP4, RELB and PHF1 in the centrosome. Localizes to spindle microtubules in metaphase and anaphase and to the midbody during cytokinesis. [ALTERNATIVE PRODUCTS] Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q9HC98-1; Sequence=Displayed; Name=2; IsoId=Q9HC98-2; Sequence=VSP_041798; Name=3; IsoId=Q9HC98-3; Sequence=VSP_041799; Name=4; IsoId=Q9HC98-4; Sequence=VSP_041800.
组织特异性Ubiquitous, with highest expression in heart and skeletal muscle. Up-regulated in a variety of malignant cancers, such as breast, colon, lung, and gastric cancers.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Protein kinase which plays an important role in mitotic cell cycle progression.Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis.Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3.
抗原信息
免疫原
A synthesized peptide: human NEK6
抗原种属
Human
基因名称
NEK6
基因ID
10783
蛋白名称
Serine/threonine-protein kinase Nek6
Uniprot ID
Q9HC98
功能
Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.
化学信息
分子量Theoretical: 36 kDa. Actual: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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