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Anti-Phospho-AURKA (Thr288) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AURKA (Thr288)。Anti-Phospho-AURKA (Thr288) Polyclonal Antibody 可用于 WB,IHC。
Anti-Phospho-AURKA (Thr288) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AURKA (Thr288)。Anti-Phospho-AURKA (Thr288) Polyclonal Antibody 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-AURKA (Thr288) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AURKA (Thr288). Anti-Phospho-AURKA (Thr288) Polyclonal Antibody can be used in WB,IHC. |
别名 | p-AURKA (Thr288), p-AURKA (T288), AURKA (p-Thr288), AURKA (p-T288) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Aurora A(Phospho-Thr288) Antibody TMAC-00350(left) or the same antibody preincubated with blocking peptide(right). 2. Western blot analysis of extracts from HT29 cells, treated with Hydroxyurea or calf intestinal phosphatase (CIP), using Aurora A (phospho-Thr288) Antibody TMAC-00350. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity By similarity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 288 (R-T-T(p)-L-M) derived from Human Aurora A |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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