购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-BLNK Antibody (2N453)

一键复制产品信息
Rating icon 还可以
货号 TMAY-02407

别名 SLP-65, SLP65, LY57, BLNK-S, B-cell linker, bca, BASH, AGM4

Anti-BLNK Antibody (2N453) 是一种 Rabbit 抗体，靶向 BLNK。Anti-BLNK Antibody (2N453) 可用于 ELISA。

Anti-BLNK Antibody (2N453)

Anti-BLNK Antibody (2N453)

一键复制产品信息
Rating icon 还可以
货号 TMAY-02407 别名 SLP-65, SLP65, LY57, BLNK-S, B-cell linker, bca, BASH, AGM4

Anti-BLNK Antibody (2N453) 是一种 Rabbit 抗体，靶向 BLNK。Anti-BLNK Antibody (2N453) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-BLNK Antibody (2N453) is a Rabbit antibody targeting BLNK. Anti-BLNK Antibody (2N453) can be used in ELISA.
别名SLP-65, SLP65, LY57, BLNK-S, B-cell linker, bca, BASH, AGM4
Ig Type
Rabbit IgG
克隆号
2N453
反应种属
Human
特异性
Human BLNK
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human BLNK / Ly-57 / SLP-65 (rh BLNK / Ly-57 / SLP-65; TMPY-02191; AAH18906.1; Met 1-Ser 456).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small intestines and colon. BLNK functions as a central linker protein that bridges kinases associated with the B-cell receptor (BCR) with a multitude of signaling pathways, regulating biological outcomes of B-cell function and development. BLNK plays a role in the activation of ERK / EPHB2, MAP kinase p38 and JNK. BLNK modulates AP1 activation. It is important for the activation of NF-kappa-B and NFAT. BLNK plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+mobilization and is required for trafficking of the BCR to late endosomes. BLNK may be required for the RAC1-JNK pathway. It plays a critical role in orchestrating the pro-B cell to pre-B cell transition. BLNK also plays an important role in BCR-induced B-cell apoptosis.Defects in BLNK are the cause of agammaglobulinemia type 4 (AGM4) which is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human BLNK / Ly-57 / SLP-65 protein (TMPY-02191)
抗原种属
Human
研究领域
Adaptor Proteins
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

  • 稀释 计算器

关键词

SLP 65LY-57LY 57AGM-4AGM 4
Related Tags: buy Anti-BLNK Antibody (2N453) | purchase Anti-BLNK Antibody (2N453) | Anti-BLNK Antibody (2N453) cost | order Anti-BLNK Antibody (2N453)