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3-Methoxytyramine hydrochloride

Name: 3-Methoxytyramine hydrochloride
Brand: TargetMol
SKU: T4710
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.18%

货号 T4710Cas号 1477-68-5

别名 3-O-甲基多巴胺盐酸盐, 3-O-methyl Dopamine hydrochloride), 3-O-methyl Dopamine hydrochloride

3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物，能够活化痕量胺相关受体1 。

3-Methoxytyramine hydrochloride

一键复制产品信息

很棒

纯度: 99.18%

货号 T4710 别名 3-O-甲基多巴胺盐酸盐, 3-O-methyl Dopamine hydrochloride), 3-O-methyl Dopamine hydrochlorideCas号 1477-68-5

3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物，能够活化痕量胺相关受体1 。

规格	价格	库存	数量
50 mg	¥ 99	现货
1 mL x 10 mM (in DMSO)	¥ 99	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

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实验操作小课堂

常见问题解答

选择批次:

纯度: 99.18%

颜色: 白色至黄色

性状: Solid

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资源下载:

COA HNMR LCMS 产品操作手册

产品介绍

3-Methoxytyramine hydrochloride AI Summary

3-Methoxytyramine hydrochloride exhibits a wide range of bioactivities across various biological assays. It has potent activity in modulating the splicing of Lamin A and demonstrates moderate potency as a lipid storage modulator in Drosophila S3 cells. Moreover, it acts as an inhibitor of alpha-Galactosidase from spleen homogenate, GCN5L2, Histone Lysine Methyltransferase G9a, Glutaminase (GLS), and HP1-beta Chromodomain interactions with methylated histone tails. Additionally, it shows activity as a delayed death inhibitor of the malarial parasite plastid and induces DNA re-replication in SW480 colon adenocarcinoma cells. The compound also functions as an agonist and desensitizer of the human trace amine associated receptor 1 (hTAAR1) and as an antagonist of nonselective Ga16 receptors. These diverse bioactivities suggest that 3-Methoxytyramine hydrochloride is a potentially versatile compound for further exploration in various biological pathways..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human brain and most tissues tissues; and in blood, cerebrospinal fluid (csf) or urine. Within a cell, 3-methoxytyramine is primarily located in the cytoplasm.
别名	3-O-甲基多巴胺盐酸盐, 3-O-methyl Dopamine hydrochloride), 3-O-methyl Dopamine hydrochloride

化学信息

分子量	203.67
分子式	C₉H₁₄ClNO₂
CAS No.	1477-68-5
Smiles	Cl.COc1cc(CCN)ccc1O
密度	no data available

储存&溶解度

存储

溶解度信息

DMSO: 250 mg/mL (1227.48 mM), Sonication is recommended.

H2O: 50 mg/mL (245.5 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.82 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.9099 mL	24.5495 mL	49.0990 mL	245.4952 mL
5 mM	0.9820 mL	4.9099 mL	9.8198 mL	49.0990 mL
10 mM	0.4910 mL	2.4550 mL	4.9099 mL	24.5495 mL
20 mM	0.2455 mL	1.2275 mL	2.4550 mL	12.2748 mL
50 mM	0.0982 mL	0.4910 mL	0.9820 mL	4.9099 mL
100 mM	0.0491 mL	0.2455 mL	0.4910 mL	2.4550 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

Inhibitor inhibit EndogenousMetabolite Endogenous Metabolite DrugMetabolite Drug Metabolite amine-associated receptor 1 (TAAR1)3-O-methyl Dopamine Hydrochloride 3-Methoxytyramine Hydrochloride 3Methoxytyramine hydrochloride 3-Methoxytyramine 3 Methoxytyramine hydrochloride

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3-Methoxytyramine hydrochloride

3-Methoxytyramine hydrochloride