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Anti-SLAMF6 Antibody (6R165)

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产品编号 TMAY-03205

Anti-SLAMF6 Antibody (6R165) 是一种 Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody (6R165) 可用于 WB。

Anti-SLAMF6 Antibody (6R165)

Anti-SLAMF6 Antibody (6R165)

Rating icon 还可以
产品编号 TMAY-03205

Anti-SLAMF6 Antibody (6R165) 是一种 Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody (6R165) 可用于 WB。

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产品介绍

生物活性
产品描述
Anti-SLAMF6 Antibody (6R165) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (6R165) can be used in WB.
Ig Type
Monoclonal Rabbit IgG
克隆号
6R165
交叉反应
Mouse
验证活性
Anti-SLAMF6 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: Mouse heart tissue lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

-Developed using the ECL technique.

-Performed under reducing conditions.

-Predicted band size:39 kDa.

-Observed band size:44 kDa
应用
WB
推荐剂量
WB: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Ly108/SLAMF6 (rM Ly108/SLAMF6; TMPY-01809; NP_109635.1; Met1-Asn239).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse Ly108/SLAMF6 Protein (TMPY-01809)
抗原种属
Mouse
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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