购物车
- 全部删除
- 您的购物车当前为空
Anti-SLAMF6 Antibody (6R165) 是一种 Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody (6R165) 可用于 WB。
Anti-SLAMF6 Antibody (6R165) 是一种 Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody (6R165) 可用于 WB。
产品描述 | Anti-SLAMF6 Antibody (6R165) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (6R165) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6R165 |
交叉反应 | Mouse |
验证活性 | Anti-SLAMF6 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Mouse heart tissue lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:39 kDa. -Observed band size:44 kDa |
应用 | WB |
推荐剂量 | WB: 1:500-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Ly108/SLAMF6 (rM Ly108/SLAMF6; TMPY-01809; NP_109635.1; Met1-Asn239). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse Ly108/SLAMF6 Protein (TMPY-01809) |
抗原种属 | Mouse |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容