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Anti-Cdc23 Antibody (5O347) 是一种 Rabbit 抗体,靶向 Cdc23。Anti-Cdc23 Antibody (5O347) 可用于 WB,ICC/IF。
Anti-Cdc23 Antibody (5O347) 是一种 Rabbit 抗体,靶向 Cdc23。Anti-Cdc23 Antibody (5O347) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-Cdc23 Antibody (5O347) is a Rabbit antibody targeting Cdc23. Anti-Cdc23 Antibody (5O347) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| 克隆号 | 5O347 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WBICC/IF |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008] |
| 免疫原 | A synthesized peptide: human CDC23 |
| 抗原种属 | Human |
| 基因名称 | CDC23 |
| 基因ID | |
| 蛋白名称 | Cell division cycle protein 23 homolog |
| Uniprot ID | |
| 功能 | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| 分子量 | Theoretical: 69 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |