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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SODD Polyclonal Antibody

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货号 TMAB-13034

Anti-SODD Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SODD。Anti-SODD Polyclonal Antibody 可用于 WB。

Anti-SODD Polyclonal Antibody

Anti-SODD Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13034

Anti-SODD Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SODD。Anti-SODD Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SODD Polyclonal Antibody is a Rabbit antibody targeting SODD. Anti-SODD Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identifiedand designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SODD
抗原种属
Human
基因名称
BAG4
基因ID
9530
蛋白名称
BAG family molecular chaperone regulator 4
Uniprot ID
O95429
功能
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling.
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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